Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | LDHB | P07195 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713219 | 0.85 | PDE7A (0.65) | PDE7ASMN1; SMN2PDE7BSLC6A2SLC6A4 | |
| SCHEMBL30338244 | 0.85 | PDE7A (0.65) | PDE7ASMN1; SMN2PDE7BSLC6A2SLC6A4 | |
| SCHEMBL1454766 | 0.83 | PDE7A (0.55) | PDE7ASMN1; SMN2PDE7BMAPTMEN1 | |
| SCHEMBL2614719 | 0.83 | PDE7A (0.59) | PDE7ASMN1; SMN2PDE7BSLC6A2SLC6A4 | |
| SCHEMBL10923003 | 0.83 | PDE7A (0.65) | PDE7ASMN1; SMN2PDE7BSLC6A2SLC6A4 | |
| SCHEMBL9186731 | 0.83 | PDE7A (0.56) | PDE7ASMN1; SMN2PDE7BSLC6A2SLC6A4 | |
| SCHEMBL8881808 | 0.83 | MAPT (0.58) | PDE7ASMN1; SMN2PDE7BSLC6A2SLC6A4 | |
| SCHEMBL7665295 | 0.83 | PDE7A (0.67) | PDE7ASMN1; SMN2PDE7BMEN1KMT2A | |
| SCHEMBL8926352 | 0.82 | MAPT (0.56) | PDE7ASMN1; SMN2PDE7BSLC6A2SLC6A4 | |
| Acetic Acid SCHEMBL8213274 | 0.81 | MAPT (0.67) | PDE7ASMN1; SMN2PDE7BSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029774-A | PHOSPHORODITHIOATES AND THEIR DERIVATIVES AND PESTICIDAL USE | ROHM AND HAAS COMPANY (US) | 1977-06-14 | — | — | US | disclosed |