Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.45 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713219 | 0.85 | PDE7A (0.65) | MAPTPDE7ASMN1; SMN2GAAPDE7B | |
| SCHEMBL30338244 | 0.85 | PDE7A (0.65) | MAPTPDE7ASMN1; SMN2GAAPDE7B | |
| SCHEMBL11760310 | 0.82 | PDE7A (0.56) | MAPTPDE7ASMN1; SMN2GAAPDE7B | |
| Acetic Acid SCHEMBL8213274 | 0.81 | MAPT (0.67) | MAPTPDE7ASMN1; SMN2GAAPDE7B | |
| SCHEMBL7665295 | 0.79 | PDE7A (0.67) | PDE7ASMN1; SMN2PDE7BMEN1KMT2A | |
| SCHEMBL2614719 | 0.79 | PDE7A (0.59) | MAPTPDE7ASMN1; SMN2PDE7BMEN1 | |
| SCHEMBL8881808 | 0.79 | MAPT (0.58) | MAPTPDE7ASMN1; SMN2PDE7BMEN1 | |
| SCHEMBL9186731 | 0.79 | PDE7A (0.56) | MAPTPDE7ASMN1; SMN2GAAPDE7B | |
| SCHEMBL10923003 | 0.79 | PDE7A (0.65) | MAPTPDE7ASMN1; SMN2PDE7BMEN1 | |
| SCHEMBL875772 | 0.77 | PDE7A (0.78) | MAPTPDE7ASMN1; SMN2GAAPDE7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620972-A | Substituted benzene derivatives | MERCK SHARP & DOHME LTD. (GB) | 1997-04-15 | — | — | US | disclosed |