Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11760297 | 0.87 | SMN1; SMN2 (0.64) | ALDH1A1MAPK14SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL11757383 | 0.87 | SMN1; SMN2 (0.64) | ALDH1A1MAPK14SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL11758347 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAPK14SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL4396197 | 0.83 | SMN1; SMN2 (0.60) | ALDH1A1MAPK14SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL4012546 | 0.81 | MAPK14 (0.56) | ALDH1A1MAPK14SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL483635 | 0.80 | CXCR3 (0.58) | ALDH1A1MAPK14SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL483633 | 0.80 | CXCR3 (0.58) | ALDH1A1MAPK14SMN1; SMN2HPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27583097 | 0.77 | HTR4 (0.60) | ALDH1A1SMN1; SMN2HPGDL3MBTL1CXCR3 | |
| SCHEMBL4005112 | 0.77 | MAPK14 (0.55) | ALDH1A1MAPK14SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL16931482 | 0.77 | SMN1; SMN2 (0.53) | ALDH1A1MAPK14SMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009208-A | N,N'-HEPTAMETHYLENEBIS(4-METHOXYBENZAMIDE) | STERLING DRUG INC. (US) | 1977-02-22 | — | — | US | disclosed |