Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757383 | 0.95 | SMN1; SMN2 (0.64) | SMN1; SMN2HPGDL3MBTL1CXCR3MMP13 | |
| SCHEMBL11760297 | 0.95 | SMN1; SMN2 (0.64) | SMN1; SMN2HPGDL3MBTL1CXCR3MMP13 | |
| SCHEMBL4005112 | 0.92 | MAPK14 (0.55) | SMN1; SMN2HPGDL3MBTL1CXCR3MMP13 | |
| SCHEMBL4012546 | 0.91 | MAPK14 (0.56) | SMN1; SMN2HPGDL3MBTL1CXCR3MMP13 | |
| SCHEMBL483633 | 0.87 | CXCR3 (0.58) | SMN1; SMN2HPGDL3MBTL1CXCR3MMP13 | |
| SCHEMBL483635 | 0.87 | CXCR3 (0.58) | SMN1; SMN2HPGDL3MBTL1CXCR3MMP13 | |
| Hydrochloric Acid SCHEMBL27583097 | 0.85 | HTR4 (0.60) | SMN1; SMN2HPGDL3MBTL1CXCR3MMP13 | |
| SCHEMBL16931482 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2HPGDL3MBTL1CXCR3MMP13 | |
| SCHEMBL5525221 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2HPGDL3MBTL1CXCR3MMP13 | |
| SCHEMBL11762802 | 0.83 | ALDH1A1 (0.60) | SMN1; SMN2HPGDL3MBTL1CXCR3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | claimed |
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ACACA, ACACB, ACAT1 | SMN1; SMN2 4702/4885HPGD 1028/4885L3MBTL1 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.