Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 6/20 | 0.43 |
| ▸ | MMP3 | P08254 | 5/20 | 0.43 |
| ▸ | MMP9 | P14780 | 4/20 | 0.43 |
| ▸ | MMP7 | P09237 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 4/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766164 | 0.84 | KCNJ1 (0.48) | LMNAMAPTKCNJ1KCNH2MMP1 | |
| SCHEMBL11762505 | 0.76 | LMNA (0.48) | LMNAMAPTKCNJ1KCNH2MMP1 | |
| SCHEMBL11768301 | 0.76 | LMNA (0.48) | LMNAMAPTKCNJ1KCNH2MMP1 | |
| SCHEMBL11762514 | 0.76 | LMNA (0.48) | LMNAMAPTKCNJ1KCNH2MMP1 | |
| SCHEMBL11760345 | 0.73 | BCHE (0.52) | KCNH2ALDH1A1 | |
| SCHEMBL16213003 | 0.69 | RAB9A (0.62) | LMNAMAPTHCRTR1HCRTR2 | |
| SCHEMBL8485172 | 0.68 | CASP3 (0.56) | KCNH2 | |
| SCHEMBL17323678 | 0.68 | CASP3 (0.51) | LMNAMMP1MMP3MMP9MMP7 | |
| SCHEMBL6325815 | 0.66 | RAB9A (0.59) | LMNAMMP1MMP3MMP9MMP7 | |
| SCHEMBL8211716 | 0.66 | RAB9A (0.59) | LMNAMMP1MMP3MMP9MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022792-A | ANALGESICS | STERLING DRUG INC. (US) | 1977-05-10 | — | — | US | disclosed |
| US-3976653-A | ANALGESIC ANTAGONIST | STERLING DRUG INC. (US) | 1976-08-24 | — | — | US | disclosed |