Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 14/20 | 0.46 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | PGK2 | P07205 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11763191 | 0.88 | FDPS (0.48) | FDPSPGK1PGK2GGPS1SMPD1 | |
| SCHEMBL11757896 | 0.84 | GGPS1 (0.55) | FDPSGGPS1SMPD1LPAR1LPAR3 | |
| SCHEMBL11763736 | 0.82 | PGK1 (0.42) | FDPSPGK1PGK2GGPS1MEN1 | |
| SCHEMBL11757262 | 0.80 | PTPN1 (0.42) | FDPS | |
| SCHEMBL11761399 | 0.79 | FDPS (0.52) | FDPSGGPS1SMPD1LPAR1LPAR3 | |
| SCHEMBL11758540 | 0.79 | ACP3 (0.46) | FDPSGGPS1MEN1ALDH1A1GAA | |
| SCHEMBL11759766 | 0.77 | GGPS1 (0.52) | FDPSGGPS1SMPD1LPAR1LPAR3 | |
| SCHEMBL11760531 | 0.75 | PTPN1 (0.49) | FDPSPGK1PGK2 | |
| SCHEMBL11761885 | 0.75 | FDPS (0.39) | FDPSPGK1PGK2GGPS1 | |
| SCHEMBL11761874 | 0.74 | PTPN1 (0.36) | FDPSPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061681-A | Method for the preparation of mono- or poly [dialkyl or dicycloalkylphosphonylmethyl] aromatic carbocyclic compounds | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |