Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 2/20 | 0.58 |
| ▸ | KLK1 | P06870 | 2/20 | 0.58 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.58 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301317 | 0.79 | NR1H4 (0.73) | NR1H4MAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11759876 | 0.76 | KCNK3 (0.59) | NR1H4RAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL12264103 | 0.75 | RAB9A (0.65) | NR1H4MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL1496348 | 0.75 | CA12 (0.58) | NR1H4RAB9ASMN1; SMN2NPC1TRPV1 | |
| SCHEMBL9083120 | 0.74 | NR1H4 (0.60) | PLGKLK1KLK6KLKB1NR1H4 | |
| Hydrochloric Acid SCHEMBL22975362 | 0.73 | PLG (1.00) | PLGKLK1KLK6KLKB1NR1H4 | |
| SCHEMBL7292373 | 0.72 | NR1H4 (0.55) | NR1H4RAB9ASMN1; SMN2NPC1TRPV1 | |
| SCHEMBL11764247 | 0.72 | PLG (0.56) | PLGKLK1KLK6KLKB1NR1H4 | |
| SCHEMBL28566157 | 0.70 | SIRT1 (0.62) | NR1H4MAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11758289 | 0.70 | MEN1 (0.49) | NR1H4MAPTRAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008274-A | ANTIFOULING | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1977-02-15 | — | — | US | disclosed |