Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | CCND3 | P30281 | 1/20 | 0.55 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250171 | 0.85 | CCND3 (0.70) | KDM4ESMN1; SMN2RAB9ANPC1CCND3 | |
| Hydrochloric Acid SCHEMBL7000982 | 0.84 | CCND3 (0.68) | KDM4ESMN1; SMN2RAB9ANPC1CCND3 | |
| SCHEMBL7199487 | 0.77 | CCND3 (0.69) | RAB9ANPC1CCND3CDK6HPGD | |
| SCHEMBL3966827 | 0.76 | CCND3 (0.67) | KDM4ESMN1; SMN2RAB9APOLBNPC1 | |
| SCHEMBL11769181 | 0.75 | RAB9A (0.67) | KDM4ESMN1; SMN2RAB9APOLBNPC1 | |
| SCHEMBL11708726 | 0.75 | NPC1 (0.66) | KDM4ESMN1; SMN2RAB9APOLBNPC1 | |
| SCHEMBL3417204 | 0.74 | CCND3 (0.60) | KDM4ESMN1; SMN2RAB9ANPC1CCND3 | |
| SCHEMBL27576939 | 0.74 | CCND3 (0.64) | RAB9ANPC1CCND3CDK6MAPT | |
| SCHEMBL5358948 | 0.73 | AURKA (0.61) | KDM4ESMN1; SMN2RAB9ANPC1CCND3 | |
| SCHEMBL29414293 | 0.73 | AURKA (0.61) | KDM4ESMN1; SMN2RAB9ANPC1CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018789-A | 5-Substituted-2-(2')-benzimidazoyl-furans | SANDOZ LTD. (CH) | 1977-04-19 | — | — | US | disclosed |