Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11765293 | 0.85 | MAPT (0.42) | ENPP2KDM4E | |
| SCHEMBL10454613 | 0.77 | FFAR1 (0.41) | ENPP2BCL2BCL2L1ALOX5MMP3 | |
| SCHEMBL625190 | 0.76 | CALM1 (0.57) | ENPP2MMP3CALM1KDM4ETDP1 | |
| SCHEMBL27675231 | 0.75 | ALDH1A1 (0.48) | ENPP2MMP3KDM4ETDP1 | |
| SCHEMBL7557664 | 0.74 | ENPP2 (0.52) | ENPP2MMP3FFAR1CALM1KDM4E | |
| SCHEMBL1514183 | 0.74 | HTR2A (0.48) | BCL2BCL2L1ALOX5HTR2ACALM1 | |
| SCHEMBL7999091 | 0.74 | ENPP2 (0.41) | ENPP2MMP3FFAR1KDM4ETDP1 | |
| SCHEMBL28594265 | 0.73 | AKR1B1 (0.52) | BCL2BCL2L1ALOX5FFAR1KDM4E | |
| SCHEMBL10410523 | 0.73 | APP (0.46) | EGFRTDP1 | |
| SCHEMBL31596156 | 0.72 | HTR2A (0.50) | BCL2BCL2L1ALOX5HTR2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874763-A | ANTIARRHYTHMIA AGENTS | ROEHM GMBH CHEMISCHE FABRIK (DE) | 1989-10-17 | — | — | US | disclosed |
| EP-0318795-A2 | Pharmaceutically active pteridin derivatives | Röhm GmbH (DE) | 1989-06-07 | — | — | EP | disclosed |