Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076496 | 0.85 | MAPT (0.38) | MAPTALDH1A1HSD17B10GAAPOLB | |
| SCHEMBL20665025 | 0.72 | TRPA1 (0.39) | MAPTALDH1A1NOTUMTRPA1ATM | |
| SCHEMBL28921705 | 0.71 | ALDH1A1 (0.42) | MAPTALDH1A1HSD17B10NOTUMTRPA1 | |
| SCHEMBL29589002 | 0.71 | HTR1A (0.53) | MAPTALDH1A1NOTUMTRPA1ATM | |
| SCHEMBL576045 | 0.71 | HTR1A (0.53) | MAPTALDH1A1NOTUMTRPA1ATM | |
| SCHEMBL29687933 | 0.71 | HTR1A (0.53) | MAPTALDH1A1NOTUMTRPA1ATM | |
| Carbamic Acid SCHEMBL11035925 | 0.69 | TRPA1 (0.50) | MAPTALDH1A1HSD17B10TRPA1ATM | |
| SCHEMBL9869690 | 0.68 | MAPT (0.44) | MAPTALDH1A1HSD17B10TRPA1ATM | |
| SCHEMBL29053925 | 0.68 | ALDH1A1 (0.38) | MAPTALDH1A1HSD17B10GAANPC1 | |
| SCHEMBL473084 | 0.68 | POLB (0.56) | MAPTALDH1A1TRPA1ATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3997549-A | INSECTICIDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1976-12-14 | — | — | US | disclosed |