Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11765549 | 0.97 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2APAX8 | |
| SCHEMBL11770736 | 0.84 | PAX8 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2APAX8 | |
| SCHEMBL11766072 | 0.81 | PAX8 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2APAX8 | |
| SCHEMBL9576023 | 0.78 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MEN1KMT2APAX8 | |
| SCHEMBL1415367 | 0.78 | MTNR1A (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL11766158 | 0.76 | CA12 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL1031875 | 0.75 | CA12 (0.46) | ALDH1A1LMNAHSD17B10MAPK1NAPEPLD | |
| SCHEMBL11765516 | 0.74 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2GAATSHRCA12 | |
| SCHEMBL11781941 | 0.74 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2APAX8 | |
| SCHEMBL22537487 | 0.73 | L3MBTL1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3981829-A | CATALYST SYSTEM OF ALKANOLAMINOTRIAZINE, HEXAHYDROTRIAZINE, A PHENOL | BASF WYANDOTTE CORPORATION (US) | 1976-09-21 | — | — | US | disclosed |