Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.38 |
| ▸ | MEN1 | O00255 | 9/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766076 | 0.89 | PPARG (0.46) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11764175 | 0.88 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11766387 | 0.86 | RXRA (0.47) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11763923 | 0.86 | MEN1 (0.39) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11763808 | 0.84 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11764459 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11767110 | 0.82 | PPARG (0.50) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11764094 | 0.81 | MAPT (0.36) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11764971 | 0.79 | AMY1A (0.38) | MAPTL3MBTL1POLBMDM2RECQL | |
| SCHEMBL11766698 | 0.78 | PPARG (0.33) | ALDH1A1MEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061771-A | Ethynylindenyl compounds and derivatives thereof used in the treatment of pain, fever and inflammation | WILLIAM H. RORER, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-3983253-A | Ethynylindenyl compounds and derivatives thereof used in the treatment of pain, fever and inflammation | WILLIAM H. RORER, INC. (US) | 1976-09-28 | — | — | US | disclosed |