Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942368 | 0.80 | PARP1 (0.47) | LMNAKDM4ESMN1; SMN2CCNE2CDK4 | |
| SCHEMBL11765410 | 0.72 | WEE1 (0.42) | CDK2CAMK2DLRRK2WEE1 | |
| SCHEMBL11711039 | 0.69 | DAO (0.47) | LMNAKDM4ESMN1; SMN2CCNE2CDK4 | |
| SCHEMBL8135955 | 0.68 | ALDH1A1 (0.41) | HPGDKDM4EPPOXCCNE2CDK4 | |
| SCHEMBL9654895 | 0.67 | ABCB11 (0.47) | — | |
| SCHEMBL5334328 | 0.66 | CDK4 (0.44) | HPGDKDM4ECCNE2CDK4CCND1 | |
| SCHEMBL3912373 | 0.66 | NQO1 (0.65) | KDM4ETP53 | |
| SCHEMBL27775823 | 0.64 | KDM4E (0.51) | HPGDKDM4ECDK4CCND1 | |
| SCHEMBL7802945 | 0.64 | GRIN2D (0.56) | LMNACYP1A2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL12822316 | 0.63 | CYP2A6 (0.39) | LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4057539-A | DYES, COLORFASTNESS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-11-08 | — | — | US | disclosed |