Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 11/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 10/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942368 | 0.77 | PARP1 (0.47) | WEE1CHEK1PARP1EGFRPRKCA | |
| SCHEMBL11420985 | 0.76 | CES1 (0.44) | WEE1CHEK1EGFRPRKCAGSK3A | |
| SCHEMBL11768950 | 0.72 | LMNA (0.42) | WEE1CDK2CAMK2DLRRK2 | |
| SCHEMBL11533447 | 0.72 | WEE1 (0.37) | WEE1CHEK1PARP1EGFRPRKCA | |
| SCHEMBL11756770 | 0.71 | PARP1 (0.45) | WEE1CHEK1PARP1GSK3AGSK3B | |
| SCHEMBL11711039 | 0.70 | DAO (0.47) | WEE1CHEK1PARP1EGFRPRKCA | |
| SCHEMBL10396142 | 0.70 | TGM2 (0.36) | WEE1CHEK1EGFRPRKCAJAK3 | |
| SCHEMBL11531116 | 0.69 | CHEK1 (0.35) | WEE1CHEK1PRKCAGSK3AGSK3B | |
| SCHEMBL5334328 | 0.67 | CDK4 (0.44) | CHEK1EGFRPRKCAGSK3AGSK3B | |
| SCHEMBL11430142 | 0.67 | CYP1A2 (0.43) | WEE1CHEK1EGFRPRKCAGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4057539-A | DYES, COLORFASTNESS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-11-08 | — | — | US | disclosed |