Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL1177066

O=C(O)C(F)(F)F.O=C1CNCCN1CCF

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 2/20 0.34
SCN9A Q15858 1/20 0.34
PKM P14618 1/20 0.33
HRH3 Q9Y5N1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1176767 0.87 ALDH1A1 (0.30) SCN9A
Trifluoroacetic Acid SCHEMBL1583669 0.87 HRH4 (0.36) HRH4SCN9APKMHRH3
Trifluoroacetic Acid SCHEMBL28429222 0.84 PIM1 (0.38) HRH4
Trifluoroacetic Acid SCHEMBL1583592 0.84 MEN1 (0.39) HRH4SCN9APKMHRH3
Trifluoroacetic Acid SCHEMBL71716 0.83 HRH4 (0.37) HRH4SCN9APKMHRH3
Trifluoroacetic Acid SCHEMBL1206539 0.83 HRH4 (0.37) HRH4SCN9APKMHRH3
Trifluoroacetic Acid SCHEMBL2352665 0.83 P2RX7 (0.39) HRH4SCN9APKMHRH3
Trifluoroacetic Acid SCHEMBL28710666 0.81 PKM (0.37) HRH4SCN9APKMHRH3
Trifluoroacetic Acid SCHEMBL28691408 0.81 PKM (0.34) HRH4SCN9APKMHRH3
Trifluoroacetic Acid SCHEMBL31571014 0.81 TSHR (0.45) HRH4PKMHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7892574-B2 In situ applying oxazolidinone to ear, skins PHARMACIA & UPJOHN COMPANY, LLC (US) 2011-02-22 US disclosed
EP-1096934-B1 OXAZOLIDINONES TO TREAT EYE INFECTIONS PHARMACIA & UPJOHN CO LLC (US) 2005-09-21 EP disclosed
EP-1304107-B1 Use of oxazolidinines derivatives for treating psoriasis PHARMACIA & UPJOHN CO LLC (US) 2005-07-06 EP disclosed
CN-1168447-C Use of oxazolidinones for the production of a medicament for the treatment of non-topical infections �������Ŷ���Լ��������˾ 2004-09-29 CN disclosed
US-6740652-B2 Oxazolidinones to treat eye infections PHARMACIA & UPJOHN COMPANY 2004-05-25 US disclosed
US-20040072841-A1 Topical administration of oxazolidinones for transdermal delivery FORD CHARLES W (US) 2004-04-15 US disclosed
US-6613349-B2 Administration of oxazolidinones for transdermal delivery PHARMACIA & UPJOHN COMPANY 2003-09-02 US disclosed
EP-1304107-A2 Use of oxazolidinines derivatives for treating psoriasis PHARMACIA & UPJOHN COMPANY (US) 2003-04-23 EP disclosed
EP-0882041-B1 PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS ASTRAZENECA AB (SE) 2003-03-26 EP disclosed
EP-1032386-B1 USE OF OXAZOLIDINONE DERIVATIVES FOR TREATING ARTHRITIS UPJOHN CO (US) 2003-02-26 EP disclosed
EP-1096934-A1 OXAZOLIDINONES TO TREAT EYE INFECTIONS PHARMACIA & UPJOHN COMPANY (US) 2001-05-09 EP disclosed
EP-1083900-A2 TOPICAL ADMINISTRATION OF OXAZOLIDINONES FOR TRANSDERMAL DELIVERY PHARMACIA & UPJOHN COMPANY (US) 2001-03-21 EP disclosed
EP-1032386-A1 USE OF OXAZOLIDINONE DERIVATITIVES FOR TREATING PSORIASIS, ARTHRITIS AND REDUCING THE TOXICITY OF CANCER CHEMOTHERAPY PHARMACIA & UPJOHN COMPANY (US) 2000-09-06 EP disclosed
US-6069145-A AGAINST ANTIBIOTIC RESISTANT BACTERIA ZENECA LIMITED (GB) 2000-05-30 US disclosed
US-6040306-A Method of treating psoriasis, arthritis and reducing the toxicity of cancer chemotherapy PHARMACIA & UPJOHN COMPANY 2000-03-21 US disclosed
WO-2000003710-A1 OXAZOLIDINONES TO TREAT EYE INFECTIONS PHARMACIA & UPJOHN COMPANY (US) 2000-01-27 WO disclosed
WO-1999062504-A2 TOPICAL ADMINISTRATION OF OXAZOLIDINONES FOR TRANSDERMAL DELIVERY PHARMACIA & UPJOHN COMPANY (US) 1999-12-09 WO disclosed
WO-1999025344-A1 USE OF OXAZOLIDINONE DERIVATIVES FOR TREATING PSORIASIS, ARTHRITIS AND REDUCING THE TOXICITY OF CANCER CHEMOTHERAPY PHARMACIA & UPJOHN COMPANY (US) 1999-05-27 WO disclosed
EP-0882041-A1 PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS AstraZeneca AB (SE) 1998-12-09 EP disclosed
WO-1997027188-A1 PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS ZENECA LIMITED (GB) 1997-07-31 WO disclosed