Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483515 | 0.89 | TSHR (0.55) | TSHRAPEX1BLMF10 | |
| Trifluoroacetic Acid SCHEMBL71716 | 0.82 | HRH4 (0.37) | TSHRHRH4PKMHRH3 | |
| Trifluoroacetic Acid SCHEMBL1206539 | 0.82 | HRH4 (0.37) | TSHRHRH4PKMHRH3 | |
| Trifluoroacetic Acid SCHEMBL28374959 | 0.82 | PKM (0.38) | F10HRH4PKMHRH3 | |
| Trifluoroacetic Acid SCHEMBL1177066 | 0.81 | HRH4 (0.34) | HRH4PKMHRH3 | |
| Trifluoroacetic Acid SCHEMBL1583669 | 0.79 | HRH4 (0.36) | HRH4PKMHRH3 | |
| Trifluoroacetic Acid SCHEMBL28434928 | 0.78 | HRH4 (0.33) | HRH4PKMHRH3 | |
| SCHEMBL3833137 | 0.77 | TSHR (0.44) | TSHRF10 | |
| Trifluoroacetic Acid SCHEMBL1583592 | 0.77 | MEN1 (0.39) | TSHRHRH4PKMHRH3 | |
| Trifluoroacetic Acid SCHEMBL28701154 | 0.77 | L3MBTL1 (0.46) | TSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101892-A1 | POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS AND USES THEREOF | Astellas Engineered Small Molecules US, Incorporated (US) | 2025-05-15 | — | — | WO | disclosed |