Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7633682 | 0.84 | TSHR (0.43) | KDM4ELMNATSHR | |
| SCHEMBL27654797 | 0.82 | KDM4E (0.53) | KDM4ELMNAHTR2CGABRR1TSHR | |
| SCHEMBL8705575 | 0.80 | — | — | |
| Methyl Aminolevulinate SCHEMBL1177850 | 0.79 | LMNA (0.80) | KDM4ELMNAHTR2CGABRR1TSHR | |
| SCHEMBL1575476 | 0.76 | KDM4E (0.47) | KDM4ELMNAHTR2CGABRR1 | |
| SCHEMBL11095630 | 0.76 | PHF8 (0.46) | KDM4ELMNAGABRR1TSHR | |
| SCHEMBL18126395 | 0.75 | TSHR (0.42) | KDM4ELMNATSHR | |
| SCHEMBL29577467 | 0.75 | TSHR (0.48) | KDM4ELMNATSHR | |
| SCHEMBL28930135 | 0.74 | PHF8 (0.45) | KDM4ELMNAGABRR1TSHR | |
| SCHEMBL9255221 | 0.73 | PAOX (0.48) | KDM4ELMNAGABRR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308830-B1 | ACID ADDITION SALTS OF 5-AMINOLEVULINIC ACID OR ITS DERIVATIVES | PHOTOCURE ASA (NO) | 2017-06-14 | — | — | EP | disclosed |
| US-8692014-B2 | Acid addition salts of 5-aminolevulinic acid or its derivatives | PHOTOCURE ASA (NO) | 2014-04-08 | — | — | US | disclosed |
| CN-1938264-B | Acid addition salts of 5-aminolevulinic acid or derivatives thereof | PHOTOCURE ASA | 2012-05-23 | — | — | CN | disclosed |
| EP-1727786-B1 | ACID ADDITION SALTS OF 5-AMINOLEVULINIC ACID OR ITS DERIVATIVES | PHOTOCURE ASA (NO) | 2011-06-29 | — | — | EP | disclosed |
| US-20110125012-A1 | ACID ADDITION SALTS OF 5-AMINOLEVULINIC ACID OR ITS DERIVATIVES | BRAENDEN JON ERIK | 2011-05-26 | — | — | US | disclosed |
| EP-2308830-A1 | Acid addition salts of 5-aminolevulinic acid or its derivatives | Photocure ASA (NO) | 2011-04-13 | — | — | EP | disclosed |
| US-7888526-B2 | Nonhygroscopic photosensitizing agents; sulphonate, hydrobromide, sulfate, nitrate and/or phosphate derivatives; diagnosing skin disorders | PHOTOCURE ASA (NO) | 2011-02-15 | — | — | US | disclosed |
| US-20080064752-A1 | Acid Addition Salts Of-5-Aminolevulinic Acid Or Its Derivatives | PHOTOCURE ASA (NO) | 2008-03-13 | — | — | US | disclosed |
| CN-1938264-A | Acid addition salts of 5-aminolevulinic acid or derivatives thereof | PHOTOCURE ASA (NO) | 2007-03-28 | — | — | CN | disclosed |
| EP-1727786-A1 | ACID ADDITION SALTS OF 5-AMINOLEVULINIC ACID OR ITS DERIVATIVES | Photocure ASA (NO) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005092838-A1 | ACID ADDITION SALTS OF 5-AMINOLEVULINIC ACID OR ITS DERIVATIVES | PHOTOCURE ASA (NO) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064752-A1 | Acid Addition Salts Of-5-Aminolevulinic Acid Or Its Derivatives | ALAD, AASDHPPT, ABAT | KDM4E 3161/4885LMNA 3222/4885HTR2C 2044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.