SCHEMBL7633682

SCHEMBL7633682

CS(=O)(=O)OC(=O)CCC(=O)OS(C)(=O)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
CA12 O43570 1/20 0.36
CA14 Q9ULX7 1/20 0.36
USP2 O75604 2/20 0.35
ALDH1A1 P00352 3/20 0.33
LMNA P02545 3/20 0.33
KDM4E B2RXH2 2/20 0.33
MMP9 P14780 1/20 0.33
ALOX15 P16050 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA1A P35348 1/20 0.33
MAPT P10636 2/20 0.32
BLM P54132 1/20 0.32
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11095630 0.90 PHF8 (0.46) TSHRALDH1A1LMNAKDM4EKDM6B
SCHEMBL29577467 0.89 TSHR (0.48) TSHRCA12CA14USP2ALDH1A1
SCHEMBL18126395 0.89 TSHR (0.42) TSHRCA12CA14USP2ALDH1A1
SCHEMBL28930135 0.88 PHF8 (0.45) TSHRALDH1A1LMNAKDM4EKDM6B
SCHEMBL2454800 0.87 ALDH1A1 (0.52) TSHRCA12CA14ALDH1A1LMNA
SCHEMBL18126348 0.87 DGKA (0.41) TSHRUSP2ALDH1A1LMNAKDM4E
SCHEMBL18126466 0.87 DGKA (0.41) TSHRUSP2ALDH1A1LMNAKDM4E
SCHEMBL1177201 0.84 KDM4E (0.55) TSHRLMNAKDM4E
SCHEMBL27639020 0.83 CES1 (0.44) TSHRCA12CA14ALDH1A1LMNA
SCHEMBL28430222 0.82 MGAM (0.39) TSHRCA12CA14USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107849493-B Defect reducing rinse solution containing ammonium salts of sulfoesters 巴斯夫欧洲公司 2020-10-09 CN claimed
CN-109996778-B Taste modifying aldehydes 高砂香料工业株式会社 2022-12-13 CN disclosed
CN-113347994-B Treatment and prevention of cancer using HER3 antigen binding molecules 蜂鸟生物科技私人有限公司 2022-09-23 CN disclosed
CN-114507285-A VISTA antigen binding molecules 蜂鸟生物科技私人有限公司 2022-05-17 CN disclosed
CN-112513080-B VISTA antigen binding molecules 蜂鸟生物科技控股有限公司 2022-03-08 CN disclosed
CN-112513095-B HER3 antigen binding molecules 蜂鸟生物科技控股有限公司 2022-03-08 CN disclosed
CN-109803948-B Warming sensation compound 高砂香料工业株式会社 2022-03-01 CN disclosed
CN-113347994-A Treatment and prevention of cancer using HER3 antigen binding molecules 蜂鸟生物科技控股私人有限公司 2021-09-03 CN disclosed
CN-112912393-A Engineered FC 蜂鸟生物科技控股私人有限公司 2021-06-04 CN disclosed
CN-112513080-A VISTA antigen binding molecules 蜂鸟生物科技控股私人有限公司 2021-03-16 CN disclosed
CN-112513095-A HER3 antigen binding molecules 蜂鸟生物科技控股私人有限公司 2021-03-16 CN disclosed
CN-107849493-B Defect reducing rinse solution containing ammonium salts of sulfoesters 巴斯夫欧洲公司 2020-10-09 CN disclosed
CN-111417653-A CD47 antigen binding molecules 蜂鸟生物科技控股私人有限公司 2020-07-14 CN disclosed
US-9130244-B2 Nonaqueous electrolyte solution and electrochemical element using same UBE INDUSTRIES, LTD. (JP) 2015-09-08 US disclosed
US-20120171581-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES, LTD. (JP) 2012-07-05 US disclosed
EP-1187805-A1 PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 2002-03-20 EP disclosed
WO-2000069808-A1 PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2000-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120171581-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME SLC8A1, OR10J3, SLC8B1 TSHR 3669/4885CA12 270/4885CA14 247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.