Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.77 |
| ▸ | CTSS | P25774 | 3/20 | 0.64 |
| ▸ | CTSK | P43235 | 3/20 | 0.64 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CTSB | P07858 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | CTSV | O60911 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11776777 | 0.90 | L3MBTL1 (0.76) | CTSLCTSSCTSKGRIA1L3MBTL1 | |
| SCHEMBL10543878 | 0.88 | GRIA1 (0.71) | CTSLCTSSCTSKGRIA1L3MBTL1 | |
| SCHEMBL10543883 | 0.88 | GRIA1 (0.71) | CTSLCTSSCTSKGRIA1L3MBTL1 | |
| SCHEMBL11773948 | 0.87 | CTSL (0.60) | CTSLCTSSCTSKGRIA1L3MBTL1 | |
| SCHEMBL6019216 | 0.87 | CTSL (1.00) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL11780493 | 0.87 | CTSL (0.73) | CTSLCTSSCTSKGRIA1L3MBTL1 | |
| Alcohol SCHEMBL19231109 | 0.86 | CTSL (0.65) | CTSLGRIA1L3MBTL1CA1CA2 | |
| SCHEMBL3404637 | 0.86 | CA2 (0.69) | CTSLGRIA1CA1CA2CA12 | |
| SCHEMBL8667639 | 0.86 | CA2 (0.69) | CTSLGRIA1CA1CA2CA12 | |
| SCHEMBL5793343 | 0.86 | CA2 (0.69) | CTSLGRIA1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |