Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.60 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778440 | 0.88 | CHRND (0.57) | CTSLL3MBTL1GRIA1 | |
| SCHEMBL11772567 | 0.87 | CTSL (0.77) | CTSLCA2CTSBCA1L3MBTL1 | |
| SCHEMBL13669574 | 0.85 | CA2 (0.70) | CTSLCA2CA1GAANPC1 | |
| SCHEMBL13669575 | 0.82 | LNPEP (0.68) | CA2CA1GAARAB9A | |
| SCHEMBL5007773 | 0.80 | GRIA1 (0.62) | CTSLGRIA1CTSSCTSK | |
| SCHEMBL5009890 | 0.80 | GRIA1 (0.62) | CTSLGRIA1CTSSCTSK | |
| SCHEMBL4373087 | 0.79 | TSHR (0.61) | CTSLGAACYP2C19RAB9AALDH1A1 | |
| SCHEMBL25641574 | 0.79 | HTT (0.54) | CA2CTSBGAAMAPTRAB9A | |
| SCHEMBL13827705 | 0.79 | GRIA1 (0.65) | GRIA1 | |
| SCHEMBL4054766 | 0.78 | CA2 (0.77) | CTSLCA2CA1L3MBTL1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |