Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 2/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11968926 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1CA12CA1 | |
| SCHEMBL1178020 | 0.82 | CA12 (0.48) | ALDH1A1CA12CA1CA2CA5A | |
| SCHEMBL12869880 | 0.81 | CYP4F2 (0.54) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL1177292 | 0.80 | TSHR (0.63) | ALDH1A1MAPTL3MBTL1CA2MEN1 | |
| SCHEMBL1177868 | 0.80 | KMT2A (0.66) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL29580771 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1CA12CA1 | |
| SCHEMBL22294680 | 0.78 | CA12 (0.55) | ALDH1A1MAPTL3MBTL1CA12CA1 | |
| SCHEMBL2395314 | 0.78 | RAB9A (0.49) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL2391690 | 0.77 | LMNA (0.49) | ALDH1A1MAPTL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL7019485 | 0.77 | F10 (0.54) | CA12CA1CA2CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019068817-A1 | ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS | INNOVATIVE MOLECULES GMBH (DE) | 2019-04-11 | — | — | WO | disclosed |
| US-7883713-B2 | Suspension, ointment, solution, spray, lotion, gel, cream, powder, powder spray, paste, emulsion, foam or stick; for treatment of herpes infections in humans | AICURIS GMBH & CO. KG (DE) | 2011-02-08 | — | — | US | disclosed |