Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11774952 | 0.98 | LMNA (0.47) | LMNAHTTRORCSMN1; SMN2MAPT | |
| SCHEMBL22337157 | 0.82 | CTDSP1 (0.56) | HTTSMN1; SMN2ALDH1A1MAPK1KMT2A | |
| SCHEMBL21609725 | 0.82 | CTDSP1 (0.56) | HTTSMN1; SMN2ALDH1A1MAPK1KMT2A | |
| SCHEMBL6825855 | 0.80 | ALDH1A1 (0.56) | LMNAMAPTALDH1A1TP53MAPK1 | |
| SCHEMBL5052716 | 0.80 | RORC (0.64) | LMNAHTTRORCSMN1; SMN2MAPT | |
| SCHEMBL11775339 | 0.79 | LMNA (0.49) | LMNAHTTRORCSMN1; SMN2MAPT | |
| SCHEMBL11777136 | 0.78 | RORC (0.50) | LMNAHTTRORCSMN1; SMN2MAPT | |
| SCHEMBL10181940 | 0.78 | RORC (0.62) | LMNAHTTRORCSMN1; SMN2MAPT | |
| SCHEMBL10181351 | 0.77 | LMNA (0.54) | LMNAHTTRORCSMN1; SMN2MAPT | |
| SCHEMBL11774946 | 0.77 | LMNA (0.46) | LMNAHTTRORCSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976672-A | INSECTICIDE | UNIROYAL INC. (US) | 1976-08-24 | — | — | US | disclosed |