Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459127 | 0.89 | ALDH1A1 (0.61) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL8555011 | 0.85 | ALDH1A1 (0.51) | ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL6825585 | 0.84 | CRBN (0.53) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL10228581 | 0.82 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL22337157 | 0.81 | CTDSP1 (0.56) | ALDH1A1TSHRKMT2AMEN1MAPK1 | |
| SCHEMBL21609725 | 0.81 | CTDSP1 (0.56) | ALDH1A1TSHRKMT2AMEN1MAPK1 | |
| SCHEMBL11774952 | 0.81 | LMNA (0.47) | ALDH1A1CYP3A4CYP2C9TSHRKMT2A | |
| SCHEMBL6822328 | 0.80 | CRBN (0.53) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL15616166 | 0.80 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL11775347 | 0.80 | LMNA (0.50) | ALDH1A1TSHRKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087643-A1 | DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME | PROMEDITECH INC. (KR) | 2004-10-14 | — | — | WO | disclosed |