Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061368 | 0.98 | ALDH1A1 (0.40) | ALDH1A1TDP1MMP8LMNAHSD17B10 | |
| SCHEMBL28077349 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TDP1MMP8LMNAHSD17B10 | |
| SCHEMBL663775 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TDP1MMP8LMNAHSD17B10 | |
| SCHEMBL230068 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TDP1MMP8LMNAHSD17B10 | |
| SCHEMBL717299 | 0.80 | ALDH1A1 (0.40) | ALDH1A1TDP1MMP8LMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL9430104 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TDP1MMP8LMNAHSD17B10 | |
| SCHEMBL28054134 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TDP1MMP8LMNAHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL27830684 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TDP1MMP8LMNAHSD17B10 | |
| SCHEMBL26658212 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TDP1MMP8LMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL27522636 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TDP1MMP8LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024061333-A1 | KRAS MUTANT PROTEIN INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 甘李药业股份有限公司 | 2024-03-28 | — | — | WO | claimed |
| CN-115996696-A | Prevention, reduction or improvement of odor of elderly people | 弗门尼舍有限公司 | 2023-04-21 | — | — | CN | claimed |
| CN-113038928-A | Preventing oxidation of flavor and food materials | 弗门尼舍有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-112979559-A | 2-phenyl pyrimidine formic acid derivative and preparation method and application thereof | 沈阳药科大学 | 2021-06-18 | — | — | CN | claimed |
| CN-112062723-A | Preparation method of thiabendazole intermediate | 帕潘纳(北京)科技有限公司 | 2020-12-11 | — | — | CN | claimed |
| CN-106748995-B | A kind of double 3,2 hydroxy pyrimidine ketones derivant and its preparation method and application | 中国工程物理研究院核物理与化学研究所 | 2019-06-18 | — | — | CN | claimed |
| CN-107602809-A | High-solid content water-based polyurethane dispersion liquid a kind of while based on aminocarboxylate and sulfamate | 温州大学 | 2018-01-19 | — | — | CN | claimed |
| CN-106748995-A | A kind of double 3,2 Hydroxypyridinone analog derivatives and its production and use | 中国工程物理研究院核物理与化学研究所 | 2017-05-31 | — | — | CN | claimed |
| EP-4561567-A2 | INHIBITORS OF PDE11A4 AND METHODS OF USING SAME | University of Maryland, Baltimore (US) | 2025-06-04 | — | — | EP | disclosed |
| CN-114174292-B | Substituted 2-morpholinopyridine derivatives as ATR kinase inhibitors | 修复治疗公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2024061333-A1 | KRAS MUTANT PROTEIN INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 甘李药业股份有限公司 | 2024-03-28 | — | — | WO | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-1894220-A | Herbicidal pyrimidines | DU PONT (US) | 2007-01-10 | — | — | CN | disclosed |
| US-7081535-B2 | Hydroxy-amino acids | BIOCATALYTICS, INC. (US) | 2006-07-25 | — | — | US | disclosed |
| US-20050192439-A1 | Methods for producing hydroxy amino acids, esters, and derivatives thereof | CODEXIS, INC. | 2005-09-01 | — | — | US | disclosed |
| US-20050100993-A1 | Methods for producing hydroxy amino acids and derivatives thereof | BIOCATALYTICS, INC. | 2005-05-12 | — | — | US | disclosed |
| US-6833471-B2 | Contacting beta-ketodiester having ketone and two esters with a ketoreductase under conditions permitting reduction of ketone to alcohol, regioselectively hydrolyzing one of ester groups to acid, converting acid or ester to amine | BIOCATALYTICS, INC. | 2004-12-21 | — | — | US | disclosed |
| US-20040053377-A1 | Methods for producing hydroxy amino acids and derivatives thereof | CODEXIS, INC. | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053377-A1 | Methods for producing hydroxy amino acids and derivatives thereof | HMGCR, HSD17B12, BCKDK | ALDH1A1 514/4885TDP1 2164/4885MMP8 2298/4885 |
| US-20050100993-A1 | Methods for producing hydroxy amino acids and derivatives thereof | ALDH7A1, BCKDK, HSD17B12 | ALDH1A1 130/4885TDP1 2778/4885MMP8 2240/4885 |
| US-20050192439-A1 | Methods for producing hydroxy amino acids, esters, and derivatives thereof | ALDH7A1, BCKDK, ADH5 | ALDH1A1 135/4885TDP1 3149/4885MMP8 2236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.