Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.73 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | MAOA | P21397 | 1/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.62 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.59 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204842 | 1.00 | HDAC3 (0.73) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL28329735 | 1.00 | HDAC3 (0.73) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| Hydrochloric Acid SCHEMBL3229769 | 0.98 | HDAC3 (0.71) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL8905341 | 0.98 | HDAC3 (0.73) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL864629 | 0.93 | HDAC3 (0.65) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL16374750 | 0.86 | ALDH1A1 (0.69) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL16727729 | 0.86 | HDAC3 (0.69) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL2224632 | 0.85 | MEN1 (0.64) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL17026711 | 0.85 | CHRM2 (0.69) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL8420591 | 0.85 | ALDH1A1 (0.68) | HDAC3HDAC1HDAC2HDAC8NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000159-A | PREPARATION OF N,N-DISUBSTITUTED THIOAMIDES | PHILLIPS PETROLEUM COMPANY (US) | 1976-12-28 | — | — | US | disclosed |