SCHEMBL7204842

SCHEMBL7204842

O=C(O)CCCCCNCc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.73
HDAC1 Q13547 2/20 0.73
HDAC2 Q92769 2/20 0.73
HDAC8 Q9BY41 2/20 0.73
NCOR2 Q9Y618 2/20 0.73
ALDH1A1 P00352 1/20 0.73
MAOA P21397 1/20 0.71
CHRM2 P08172 1/20 0.69
SIGMAR1 Q99720 3/20 0.62
FOLH1 Q04609 1/20 0.59
MAPT P10636 1/20 0.59
RXFP1 Q9HBX9 1/20 0.59
S1PR1 P21453 2/20 0.59
S1PR3 Q99500 2/20 0.59
S1PR2 O95136 1/20 0.59
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
TDP1 Q9NUW8 1/20 0.55
BCHE P06276 1/20 0.54
ACHE P22303 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28329735 1.00 HDAC3 (0.73) HDAC3HDAC1HDAC2HDAC8NCOR2
SCHEMBL11775902 1.00 HDAC3 (0.73) HDAC3HDAC1HDAC2HDAC8NCOR2
Hydrochloric Acid SCHEMBL3229769 0.98 HDAC3 (0.71) HDAC3HDAC1HDAC2HDAC8NCOR2
SCHEMBL8905341 0.98 HDAC3 (0.73) HDAC3HDAC1HDAC2HDAC8NCOR2
SCHEMBL864629 0.93 HDAC3 (0.65) HDAC3HDAC1HDAC2HDAC8NCOR2
SCHEMBL16374750 0.86 ALDH1A1 (0.69) HDAC3HDAC1HDAC2HDAC8NCOR2
SCHEMBL16727729 0.86 HDAC3 (0.69) HDAC3HDAC1HDAC2HDAC8NCOR2
SCHEMBL2224632 0.85 MEN1 (0.64) HDAC3HDAC1HDAC2HDAC8NCOR2
SCHEMBL17026711 0.85 CHRM2 (0.69) HDAC3HDAC1HDAC2HDAC8NCOR2
SCHEMBL8420591 0.85 ALDH1A1 (0.68) HDAC3HDAC1HDAC2HDAC8NCOR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110423201-B Method for synthesizing hexamethylene diamine by using caprolactam as raw material 郑州大学 2022-07-12 CN disclosed
CN-110423201-A A method of using caprolactam as Material synthesis hexamethylene diamine UNIV ZHENGZHOU 2019-11-08 CN disclosed
EP-0699745-B1 Automatic dishwashing compositions comprising quaternary ammonium compounds bleach activators and quaternary ammonium UNIV NORTH CAROLINA STATE (US) 2003-05-14 EP disclosed
US-5654421-A WASHING KITCHENWARE THE PROCTER & GAMBLE COMPANY (US) 1997-08-05 US disclosed
US-5578136-A AND A SOURCE OF HYDROGEN PEROXIDE; REMOVE TEA STAINS THE PROCTER & GAMBLE COMPANY (US) 1996-11-26 US disclosed
EP-0699745-A2 Automatic dishwashing compositions comprising quaternary ammonium compounds bleach activators and quaternary ammonium THE PROCTER & GAMBLE COMPANY (US) 1996-03-06 EP disclosed