Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | ACLY | P53396 | 2/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11784962 | 0.92 | L3MBTL1 (0.46) | L3MBTL1CISD1JAK3IRAK4HPGD | |
| SCHEMBL11781725 | 0.87 | GAA (0.43) | L3MBTL1CISD1HPGDHSD17B10KDM4E | |
| SCHEMBL11777320 | 0.86 | CISD1 (0.49) | L3MBTL1CISD1JAK3IRAK4HPGD | |
| SCHEMBL11841803 | 0.85 | L3MBTL1 (0.50) | L3MBTL1HDAC1CISD1JAK3IRAK4 | |
| SCHEMBL11780536 | 0.82 | BDKRB1 (0.41) | L3MBTL1SMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL11781708 | 0.80 | MEN1 (0.48) | L3MBTL1KDM4EMAPTALDH1A1POLB | |
| SCHEMBL11841241 | 0.79 | CISD1 (0.53) | L3MBTL1CISD1JAK3IRAK4HPGD | |
| SCHEMBL11843466 | 0.78 | ALDH1A1 (0.52) | L3MBTL1HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL11777521 | 0.78 | ALDH1A1 (0.45) | CISD1HPGDHSD17B10KDM4EAPP | |
| SCHEMBL11846910 | 0.77 | CISD1 (0.48) | L3MBTL1HDAC1CISD1JAK3IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |