Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841803 | 0.92 | L3MBTL1 (0.50) | L3MBTL1KMT2AMEN1GPR55PTK2B | |
| SCHEMBL11780992 | 0.92 | L3MBTL1 (0.41) | L3MBTL1KMT2AMEN1GPR55PTK2B | |
| SCHEMBL11777320 | 0.89 | CISD1 (0.49) | L3MBTL1CISD1JAK3IRAK4LMNA | |
| SCHEMBL11781708 | 0.88 | MEN1 (0.48) | L3MBTL1KMT2AMEN1GPR55PTK2B | |
| SCHEMBL11777521 | 0.85 | ALDH1A1 (0.45) | KMT2AMEN1CISD1LMNAMAPT | |
| SCHEMBL11841241 | 0.82 | CISD1 (0.53) | L3MBTL1CISD1JAK3IRAK4LMNA | |
| SCHEMBL11780536 | 0.81 | BDKRB1 (0.41) | L3MBTL1KMT2AMEN1HTTLMNA | |
| SCHEMBL11846910 | 0.80 | CISD1 (0.48) | L3MBTL1HTTCISD1JAK3IRAK4 | |
| SCHEMBL11853856 | 0.80 | CISD1 (0.54) | L3MBTL1KMT2AMEN1CISD1JAK3 | |
| SCHEMBL11845448 | 0.80 | ALOX15 (0.47) | KMT2AMEN1LMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |