Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4845235 | 0.86 | GPR35 (0.47) | ALDH1A1HTTMAPTTDP1LMNA | |
| SCHEMBL11775275 | 0.83 | ALDH1A1 (0.51) | ALDH1A1HTTMAPTTDP1SMN1; SMN2 | |
| SCHEMBL11777721 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HTTMAPTTDP1LMNA | |
| SCHEMBL4543292 | 0.82 | ALDH1A1 (0.64) | ALDH1A1HTTMAPTTDP1LMNA | |
| SCHEMBL28276151 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HTTMAPTTDP1LMNA | |
| SCHEMBL4364077 | 0.80 | POLB (0.48) | ALDH1A1HTTMAPTTDP1LMNA | |
| SCHEMBL10717379 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HTTTDP1MEN1KMT2A | |
| SCHEMBL24155814 | 0.76 | MAPT (0.73) | ALDH1A1HTTMAPTTDP1LMNA | |
| SCHEMBL10853274 | 0.76 | EPAS1 (0.55) | ALDH1A1HTTMAPTTDP1F10 | |
| SCHEMBL10854114 | 0.75 | ALDH1A1 (0.70) | ALDH1A1HTTMAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3944575-A | Aryl ether compounds and their synthesis | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1976-03-16 | — | — | US | disclosed |