Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | LMNA | P02545 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4843320 | 0.89 | GPR35 (0.51) | GPR35MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL11778043 | 0.86 | ALDH1A1 (0.51) | MAPTLMNAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL4840927 | 0.84 | GPR35 (0.53) | GPR35MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL4845296 | 0.83 | GPR35 (0.49) | GPR35MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL4847049 | 0.82 | GPR35 (0.58) | GPR35MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL28760189 | 0.80 | HPSE (0.49) | GPR35TDP1F10MEN1KMT2A | |
| SCHEMBL7583285 | 0.80 | GPR35 (0.51) | GPR35ALDH1A1TDP1CTSBF10 | |
| SCHEMBL4847624 | 0.80 | GPR35 (0.51) | GPR35MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL4839671 | 0.79 | GPR35 (0.55) | GPR35MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL27657688 | 0.79 | F10 (0.42) | GPR35MAPTLMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365231-B2 | Compound with antitumor activity and preparation method therefor | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2008-04-29 | — | — | US | disclosed |
| US-20060241187-A1 | Compound with antitumor activity and preparation method therefor | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241187-A1 | Compound with antitumor activity and preparation method therefor | WEE1, WEE2, CYP51A1 | GPR35 2929/4885MAPT 4457/4885LMNA 2945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.