Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11775275 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HTTF10HSPB1KMT2A | |
| SCHEMBL11778043 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HTTF10HSPB1KMT2A | |
| SCHEMBL4543292 | 0.79 | ALDH1A1 (0.64) | ALDH1A1HTTHSPB1KMT2AMEN1 | |
| SCHEMBL1864453 | 0.78 | HPGD (0.64) | ALDH1A1HTTHSPB1KMT2AMEN1 | |
| SCHEMBL10717379 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HTTKMT2AMEN1TDP1 | |
| SCHEMBL11777721 | 0.76 | ALDH1A1 (0.57) | ALDH1A1HTTF10KMT2AMEN1 | |
| SCHEMBL4843320 | 0.74 | GPR35 (0.51) | ALDH1A1HTTF10HSPB1KMT2A | |
| SCHEMBL17086981 | 0.74 | HSPB1 (0.57) | ALDH1A1HSPB1KMT2AMEN1TDP1 | |
| SCHEMBL10854114 | 0.73 | ALDH1A1 (0.70) | ALDH1A1HTTHSPB1KMT2AMEN1 | |
| SCHEMBL3847171 | 0.73 | ALDH1A1 (0.52) | ALDH1A1HTTKMT2AL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384764-B | Phenyl thiophene sulfonamide compound, pharmaceutical composition, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2021-09-03 | — | — | CN | disclosed |
| CN-109384764-A | Tolylthiophene sulfamide compound, pharmaceutical composition, preparation method and application | 中国科学院上海有机化学研究所 | 2019-02-26 | — | — | CN | disclosed |