Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 6/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11782429 | 0.84 | OPRD1 (0.41) | MAOBMAOAOPRD1KCNH2SIGMAR1 | |
| SCHEMBL11783875 | 0.84 | PRCP (0.46) | MAOBMAOAOPRD1KCNH2SIGMAR1 | |
| SCHEMBL11781081 | 0.84 | PRCP (0.42) | MAOBOPRD1KCNH2SIGMAR1DRD2 | |
| SCHEMBL11781143 | 0.84 | SIGMAR1 (0.51) | OPRD1KCNH2SIGMAR1DRD2PRCP | |
| SCHEMBL11846381 | 0.80 | OPRD1 (0.37) | OPRD1KCNH2SIGMAR1ADRA2A | |
| SCHEMBL11778772 | 0.80 | OPRD1 (0.47) | OPRD1KCNH2SIGMAR1DRD2PRCP | |
| SCHEMBL11780816 | 0.78 | OPRD1 (0.41) | MAOBOPRD1KCNH2SIGMAR1DRD2 | |
| SCHEMBL11781010 | 0.78 | PRCP (0.43) | MAOBMAOAPRCP | |
| SCHEMBL11781464 | 0.78 | OPRD1 (0.45) | MAOBOPRD1KCNH2SIGMAR1PRCP | |
| SCHEMBL11778403 | 0.77 | OPRD1 (0.47) | OPRD1KCNH2SIGMAR1DRD2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3980786-A | 1,3-Dihydro-3-phenyl-1'-(2-propynyl)spiro[isobenzofuran]s | AMERICAN HOECHST CORPORATION (US) | 1976-09-14 | — | — | US | disclosed |