Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 9/20 | 0.41 |
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11783875 | 0.93 | PRCP (0.46) | PRCPMAOBMAOA | |
| SCHEMBL11781772 | 0.89 | PRCP (0.52) | PRCP | |
| SCHEMBL11855307 | 0.81 | SIGMAR1 (0.53) | PRCP | |
| SCHEMBL11854306 | 0.81 | PRCP (0.41) | PRCP | |
| SCHEMBL11782429 | 0.80 | OPRD1 (0.41) | PRCPMAOBMAOA | |
| SCHEMBL11781143 | 0.79 | SIGMAR1 (0.51) | PRCP | |
| SCHEMBL11778295 | 0.78 | MAOB (0.40) | PRCPMAOBMAOA | |
| SCHEMBL11781081 | 0.78 | PRCP (0.42) | PRCPMAOB | |
| SCHEMBL11780509 | 0.77 | SIGMAR1 (0.45) | PRCP | |
| SCHEMBL11781464 | 0.77 | OPRD1 (0.45) | PRCPMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3980786-A | 1,3-Dihydro-3-phenyl-1'-(2-propynyl)spiro[isobenzofuran]s | AMERICAN HOECHST CORPORATION (US) | 1976-09-14 | — | — | US | disclosed |