Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | EBP | Q15125 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11775911 | 0.83 | CHRM2 (0.51) | CHRM2HRH3ACACBEBPSIGMAR1 | |
| SCHEMBL11777823 | 0.83 | CHRM2 (0.51) | CHRM2HRH3ACACBEBPSIGMAR1 | |
| SCHEMBL11779573 | 0.82 | CHRM2 (0.54) | CHRM2HRH3ACACBEBPSIGMAR1 | |
| SCHEMBL11778440 | 0.81 | CHRND (0.57) | L3MBTL1CTSL | |
| SCHEMBL7300651 | 0.76 | ITGB3 (0.66) | CHRM2HRH3ACACBLMNA | |
| SCHEMBL11773882 | 0.75 | MCHR1 (0.50) | CHRM2HRH3ACACB | |
| SCHEMBL13631848 | 0.75 | KLKB1 (0.55) | PLGL3MBTL1CTSLKLKB1NPC1 | |
| SCHEMBL11826987 | 0.75 | ITGB3 (0.58) | CHRM2HRH3ACACBEBPSIGMAR1 | |
| SCHEMBL3867760 | 0.75 | MCHR1 (0.62) | HRH3NPC1 | |
| Tiropramide SCHEMBL25693 | 0.74 | LMNA (0.54) | CHRM2HRH3ACACBAVPR1AEBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |