Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | EBP | Q15125 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11777823 | 0.89 | CHRM2 (0.51) | CHRM2HRH3ACACBEBPSIGMAR1 | |
| SCHEMBL11775911 | 0.89 | CHRM2 (0.51) | CHRM2HRH3ACACBEBPSIGMAR1 | |
| SCHEMBL11779578 | 0.82 | PLG (0.51) | CHRM2HRH3ACACBEBPSIGMAR1 | |
| SCHEMBL11781869 | 0.81 | CTSL (0.48) | ITGB3ITGA2BCA2GAARAB9A | |
| SCHEMBL11773882 | 0.80 | MCHR1 (0.50) | CHRM2HRH3ACACBITGB3ITGA2B | |
| SCHEMBL11777766 | 0.80 | CHRM2 (0.49) | CHRM2HRH3ACACBEBPSIGMAR1 | |
| SCHEMBL11777095 | 0.79 | ITGB3 (0.50) | CHRM2HRH3ACACBITGB3ITGA2B | |
| SCHEMBL11780603 | 0.79 | ITGB3 (0.50) | CHRM2HRH3ACACBITGB3ITGA2B | |
| SCHEMBL11778432 | 0.79 | CA2 (0.52) | ITGB3ITGA2BCA2GAARAB9A | |
| SCHEMBL11826987 | 0.79 | ITGB3 (0.58) | CHRM2HRH3ACACBEBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |