Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 3/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL11780008 | 1.00 | KCNH2 (0.34) | KCNH2GNAI3GNAO1GNAI1CCR5 | |
| SCHEMBL2266931 | 0.98 | KCNH2 (0.35) | KCNH2GNAI3GNAO1GNAI1CCR5 | |
| SCHEMBL2267102 | 0.98 | KCNH2 (0.35) | KCNH2GNAI3GNAO1GNAI1CCR5 | |
| Hydrochloric Acid SCHEMBL11786483 | 0.96 | CCR5 (0.36) | KCNH2GNAI3GNAO1GNAI1CCR5 | |
| Hydrochloric Acid SCHEMBL9715248 | 0.96 | CCR5 (0.36) | KCNH2GNAI3GNAO1GNAI1CCR5 | |
| SCHEMBL1029399 | 0.84 | FUT7 (0.36) | KCNH2ALDH1A1HPGDTSHRTHRA | |
| SCHEMBL1027683 | 0.84 | FUT7 (0.36) | KCNH2ALDH1A1HPGDTSHRTHRA | |
| Iodide SCHEMBL11342432 | 0.76 | GNAI3 (0.33) | GNAI3GNAO1GNAI1CCR5SPHK1 | |
| SCHEMBL7585200 | 0.73 | CA1 (0.33) | GNAI3GNAO1GNAI1CCR5EEF2K | |
| Water SCHEMBL2392672 | 0.72 | ALDH1A1 (0.36) | GNAI3GNAO1GNAI1EEF2KALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931129-A | FLUOROELASTOMER COMPOSITION | DAIKIN KOGYO CO., LTD. (JA) | 1976-01-06 | — | — | US | disclosed |