Hydrochloric Acid

Hydrochloric Acid

SCHEMBL9715248

CCCCCCCCCC1=[N+](C)CCN1C.[Cl-]

nearest known ligand 0.36

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Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR5 P51681 5/20 0.36
KCNH2 Q12809 2/20 0.34
GNAI3 P08754 1/20 0.34
GNAO1 P09471 1/20 0.34
GNAI1 P63096 1/20 0.34
SPHK1 Q9NYA1 4/20 0.33
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
HSP90AA1 P07900 1/20 0.31
CYP3A4 P08684 1/20 0.31
G6PD P11413 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
SPHK2 Q9NRA0 2/20 0.30
EEF2K O00418 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11786483 1.00 CCR5 (0.36) CCR5KCNH2GNAI3GNAO1GNAI1
SCHEMBL2267102 0.98 KCNH2 (0.35) CCR5KCNH2GNAI3GNAO1GNAI1
SCHEMBL2266931 0.98 KCNH2 (0.35) CCR5KCNH2GNAI3GNAO1GNAI1
Iodide SCHEMBL11780477 0.96 KCNH2 (0.34) CCR5KCNH2GNAI3GNAO1GNAI1
Iodide SCHEMBL11780008 0.96 KCNH2 (0.34) CCR5KCNH2GNAI3GNAO1GNAI1
SCHEMBL1027683 0.84 FUT7 (0.36) KCNH2ALDH1A1HPGDTSHRTHRA
SCHEMBL1029399 0.84 FUT7 (0.36) KCNH2ALDH1A1HPGDTSHRTHRA
Hydrochloric Acid SCHEMBL10704080 0.76 CCR5 (0.33) CCR5GNAI3GNAO1GNAI1SPHK1
Hydrochloric Acid SCHEMBL7750994 0.76 GNAI3 (0.37) CCR5KCNH2GNAI3GNAO1GNAI1
SCHEMBL7585200 0.73 CA1 (0.33) CCR5GNAI3GNAO1GNAI1SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0500712-A1 COMBATTING SLIME-FORMING MICROORGANISMS Henkel Kommanditgesellschaft auf Aktien (DE) 1992-09-02 EP disclosed
WO-1991007090-A1 COMBATTING SLIME-FORMING MICROORGANISMS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1991-05-30 WO disclosed