Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
| ▸ | PRCP | P42785 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | EBP | Q15125 | 1/20 | 0.51 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11860134 | 0.89 | PRCP (0.52) | SIGMAR1GRIN2DGRIN3BDRD2GRIN1 | |
| SCHEMBL11684907 | 0.82 | SIGMAR1 (0.70) | SIGMAR1PRCPOPRM1OPRK1OPRD1 | |
| SCHEMBL11783875 | 0.81 | PRCP (0.46) | SIGMAR1DRD2PRCPOPRD1 | |
| SCHEMBL11781010 | 0.81 | PRCP (0.43) | PRCP | |
| SCHEMBL11853169 | 0.81 | PRCP (0.45) | SIGMAR1PRCPOPRM1OPRK1OPRD1 | |
| SCHEMBL12175470 | 0.80 | PRCP (0.69) | SIGMAR1PRCPOPRM1OPRK1OPRD1 | |
| SCHEMBL11854306 | 0.80 | PRCP (0.41) | SIGMAR1DRD2PRCPOPRD1 | |
| SCHEMBL11876027 | 0.78 | PKM (0.49) | PRCP | |
| SCHEMBL11863710 | 0.75 | SIGMAR1 (0.60) | SIGMAR1OPRM1OPRK1OPRD1EBP | |
| SCHEMBL3750826 | 0.74 | HTR2C (0.35) | SIGMAR1PRCPOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |