Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CDC42 | P60953 | 1/20 | 0.59 |
| ▸ | RAC1 | P63000 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20325965 | 0.85 | PARP10 (0.49) | ALOX5AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL11778937 | 0.85 | AKR1C3 (0.71) | ALOX5AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL5528055 | 0.84 | CA1 (0.53) | ALOX5 | |
| SCHEMBL15517793 | 0.84 | CA1 (0.53) | ALOX5 | |
| SCHEMBL9119592 | 0.83 | PTGS2 (0.73) | ALOX5AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL30380801 | 0.83 | PTGS2 (0.73) | ALOX5AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL30760568 | 0.83 | PTGS2 (0.73) | ALOX5AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL263373 | 0.83 | PTGS2 (0.73) | ALOX5AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL1478228 | 0.83 | PTGS2 (0.73) | ALOX5AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL11783271 | 0.82 | ALOX5 (0.58) | ALOX5AKR1C3AKR1C2PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931269-A | ANTIINFLAMMATORY | WILLIAM H. RORER, INC. (US) | 1976-01-06 | — | — | US | disclosed |