Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | PTPRG | P23470 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11773180 | 0.82 | RAB9A (0.50) | KDM4ECYP1A2RAB9APOLBMEN1 | |
| SCHEMBL11777753 | 0.81 | KEAP1 (0.46) | KDM4ECYP1A2RAB9APOLBNPC1 | |
| SCHEMBL11772304 | 0.81 | RAB9A (0.49) | KDM4ECYP1A2MYCNR4A1RAB9A | |
| SCHEMBL11774864 | 0.78 | SMN1; SMN2 (0.53) | KDM4ECYP1A2APEX1RAB9APOLB | |
| SCHEMBL11770114 | 0.78 | KDM4E (0.53) | KDM4EGLACYP1A2MYCNR4A1 | |
| SCHEMBL5237193 | 0.77 | KDM4E (0.57) | KDM4EGLACYP1A2MYCNR4A1 | |
| SCHEMBL11774987 | 0.77 | RAB9A (0.67) | CYP1A2PTPRCPTPRGRAB9APOLB | |
| SCHEMBL2561504 | 0.76 | CYP1A2 (0.73) | CYP1A2RAB9APOLBMEN1KMT2A | |
| SCHEMBL19967189 | 0.74 | KDM4E (0.58) | KDM4EGLACYP1A2MYCNR4A1 | |
| SCHEMBL11818393 | 0.74 | KMT2A (0.60) | KDM4EGLAPTPRCPTPRGPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953595-A | Substituted benzoic acid hypolipemic agents | PFIZER INC. (US) | 1976-04-27 | — | — | US | disclosed |