Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | PTPRG | P23470 | 3/20 | 0.54 |
| ▸ | PTPRC | P08575 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820877 | 0.88 | PTPRG (0.69) | KMT2AMEN1PTPRGPTPRCAR | |
| SCHEMBL11820863 | 0.82 | KMT2A (0.48) | KMT2AMEN1PTPRGPTPRCPTGDR2 | |
| SCHEMBL11812476 | 0.81 | PTPRG (0.60) | KMT2AMEN1PTPRGPTPRCAR | |
| SCHEMBL11815274 | 0.80 | MRGPRX4 (0.53) | KMT2AMEN1PTPRGPTPRCAR | |
| SCHEMBL15788318 | 0.79 | AKR1C2 (0.52) | KMT2AMEN1 | |
| SCHEMBL30016005 | 0.79 | PTPRC (0.68) | KMT2AMEN1PTPRGPTPRCHPGD | |
| SCHEMBL11819918 | 0.78 | KMT2A (0.47) | KMT2AMEN1PTPRGPTPRCALDH1A1 | |
| SCHEMBL11821805 | 0.76 | KMT2A (0.45) | KMT2AMEN1PTPRGPTPRCALDH1A1 | |
| SCHEMBL11825334 | 0.76 | KMT2A (0.43) | KMT2AMEN1PTPRGPTPRCPTGDR2 | |
| SCHEMBL14426616 | 0.75 | MEN1 (1.00) | KMT2AMEN1KDM4EL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |