Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11844003 | 0.98 | HTR6 (0.52) | HTR6L3MBTL1GPR84HPGDNCF1 | |
| SCHEMBL3584996 | 0.86 | HTR6 (0.58) | HTR6GPR84NCF1IMPDH2ALDH1A1 | |
| SCHEMBL23536600 | 0.76 | HTR6 (0.51) | HTR6L3MBTL1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL9237227 | 0.76 | CDC25A (0.49) | — | |
| SCHEMBL1413286 | 0.74 | HTR6 (0.47) | HTR6L3MBTL1HPGDNCF1ALDH1A1 | |
| SCHEMBL27249997 | 0.74 | BRD4 (0.44) | L3MBTL1GPR84IMPDH2ALDH1A1 | |
| SCHEMBL27249985 | 0.73 | POLB (0.41) | L3MBTL1GPR84IMPDH2ALDH1A1GAA | |
| SCHEMBL27249582 | 0.72 | BRD4 (0.48) | GPR84HPGDIMPDH2ALDH1A1 | |
| SCHEMBL28872984 | 0.72 | GPR84 (0.50) | GPR84IMPDH2ALDH1A1LMNAHTR2A | |
| SCHEMBL18508878 | 0.71 | GAA (0.44) | HTR6L3MBTL1ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3993764-A | 3-(4*-PIPERIDYL)-INDOLES | ROUSSEL-UCLAF (FR) | 1976-11-23 | — | — | US | claimed |
| US-3993764-A | 3-(4*-PIPERIDYL)-INDOLES | ROUSSEL-UCLAF (FR) | 1976-11-23 | — | — | US | disclosed |
| US-3947578-A | Omega-[4-(3\"-indolyl)-piperidino]-alkyl-arylketones as nevroleptics | ROUSSEL UCLAF (FR) | 1976-03-30 | — | — | US | disclosed |