Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | PRKCB | P05771 | 3/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | PRKCA | P17252 | 2/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786609 | 0.86 | HTR6 (0.54) | HTR6LMNAGLAGPR84HTR2A | |
| Hydrochloric Acid SCHEMBL11844003 | 0.84 | HTR6 (0.52) | HTR6LMNAGLAGPR84NCF1 | |
| SCHEMBL26408376 | 0.78 | KMT2A (0.46) | HTR6CYP3A4CYP2D6HTTLMNA | |
| SCHEMBL3596171 | 0.77 | DRD2 (0.58) | HTR6TSHRHTTADRA2CLMNA | |
| SCHEMBL20784110 | 0.77 | KDM4E (0.54) | HTR6CYP3A4CYP2D6HTTADRA2C | |
| SCHEMBL1413404 | 0.77 | HTR6 (0.50) | HTR6CYP3A4CYP2D6TSHRHTT | |
| SCHEMBL25675827 | 0.74 | KMT2A (0.41) | HTR6CYP3A4CYP2D6HTTALDH1A1 | |
| SCHEMBL25691582 | 0.74 | HTR1A (0.42) | HTR6CYP3A4CYP2D6TSHRHTT | |
| SCHEMBL28872984 | 0.72 | GPR84 (0.50) | HTTLMNAGPR84HTR2AIMPDH2 | |
| SCHEMBL20784109 | 0.71 | SIRT6 (0.52) | CYP3A4CYP2D6HTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029636-A1 | Lck inhibitors | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029636-A1 | Lck inhibitors | LCK, ZAP70, FYN | HTR6 4108/4885CYP3A4 3372/4885CYP2D6 2093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.