SCHEMBL117885

SCHEMBL117885

CO[C@@H]1C[C@H](C)CC[C@H]1C(C)C

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TRPA1 O75762 2/20 0.52
TRPM8 Q7Z2W7 2/20 0.52
EPHX1 P07099 3/20 0.47
LMNA P02545 2/20 0.46
NFE2L2 Q16236 1/20 0.45
HPGD P15428 1/20 0.43
CYP19A1 P11511 2/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
KDM4E B2RXH2 1/20 0.42
APOBEC3A P31941 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42
GAA P10253 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
P2RX4 Q99571 1/20 0.39
NTSR1 P30989 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2954664 1.00 ALDH1A1 (0.54) ALDH1A1TRPA1TRPM8EPHX1LMNA
SCHEMBL14037202 1.00 ALDH1A1 (0.54) ALDH1A1TRPA1TRPM8EPHX1LMNA
SCHEMBL14515031 1.00 ALDH1A1 (0.54) ALDH1A1TRPA1TRPM8EPHX1LMNA
SCHEMBL13927583 1.00 ALDH1A1 (0.54) ALDH1A1TRPA1TRPM8EPHX1LMNA
SCHEMBL14515030 1.00 ALDH1A1 (0.54) ALDH1A1TRPA1TRPM8EPHX1LMNA
SCHEMBL2609249 1.00 ALDH1A1 (0.54) ALDH1A1TRPA1TRPM8EPHX1LMNA
SCHEMBL3338174 1.00 ALDH1A1 (0.54) ALDH1A1TRPA1TRPM8EPHX1LMNA
SCHEMBL115394 1.00 ALDH1A1 (0.54) ALDH1A1TRPA1TRPM8EPHX1LMNA
SCHEMBL21610687 1.00 ALDH1A1 (0.54) ALDH1A1TRPA1TRPM8EPHX1LMNA
SCHEMBL13206675 1.00 ALDH1A1 (0.54) ALDH1A1TRPA1TRPM8EPHX1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1094 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110869365-B Cooling composition 弗门尼舍有限公司 2024-03-29 CN claimed
US-20240000746-A1 New Cooling Agents and Preparations Containing Them SYMRISE AG (DE) 2024-01-04 US claimed
CN-112645803-B Synthetic method of menthol methyl ether 厦门中坤化学有限公司 2023-10-20 CN claimed
EP-4247791-A2 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2023-09-27 EP claimed
CN-116685575-A Novel cooling substances and formulations containing these cooling substances 西姆莱斯股份公司 2023-09-01 CN claimed
WO-2023143741-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 WO claimed
WO-2023144326-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 WO claimed
WO-2023117119-A1 ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-06-29 WO claimed
EP-4015075-A1 STANDARD PACKAGES WITH FIXED COOLING MATERIALS Symrise AG (DE) 2022-06-22 EP claimed
WO-2022105986-A1 NOVEL COOLING AGENTS AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2022-05-27 WO claimed
US-20040253278-A1 Breath Freshening and Oral Cleansing Product Using Carvacrol WM WRIGLEY JR. COMPANY 2004-12-16 US claimed
US-20040253189-A1 Breath Freshening and Oral Cleansing Product Using Geraniol WM. WRIGLEY JR. COMPANY 2004-12-16 US claimed
US-20040253190-A1 Breath Freshening and Oral Cleansing Product Using Citral WM. WRIGLEY JR. COMPANY 2004-12-16 US claimed
US-20040253192-A1 Breath Freshening and Oral Cleansing Product Using Cardamom Oil WM. WRIGLEY JR. COMPANY 2004-12-16 US claimed
WO-2004019867-A2 BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING CARDAMOM OIL WM. WRIGLEY JR. COMPANY (US) 2004-03-11 WO claimed
WO-2004019800-A2 BREATH FRESHENING AND ORAL CLEANSING PRODUCT WM. WRIGLEY JR. COMPANY (US) 2004-03-11 WO claimed
WO-2004019870-A2 BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING SALICYLALDEHYDE WM. WRIGLEY JR. COMPANY (US) 2004-03-11 WO claimed
WO-2004019922-A1 BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING CITRAL WM. WRIGLEY JR. COMPANY (US) 2004-03-11 WO claimed
WO-2004019871-A2 BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING GERANIOL WM. WRIGLEY JR. COMPANY (US) 2004-03-11 WO claimed
WO-2004019802-A2 BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING CARVACROL WM. WRIGLEY JR. COMPANY (US) 2004-03-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240000746-A1 New Cooling Agents and Preparations Containing Them TTPA, TREH, TAS2R45 ALDH1A1 1658/4885TRPA1 313/4885TRPM8 132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.