Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14037202 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TRPA1TRPM8EPHX1LMNA | |
| SCHEMBL14515031 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TRPA1TRPM8EPHX1LMNA | |
| SCHEMBL13927583 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TRPA1TRPM8EPHX1LMNA | |
| SCHEMBL14515030 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TRPA1TRPM8EPHX1LMNA | |
| SCHEMBL2609249 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TRPA1TRPM8EPHX1LMNA | |
| SCHEMBL117885 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TRPA1TRPM8EPHX1LMNA | |
| SCHEMBL3338174 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TRPA1TRPM8EPHX1LMNA | |
| SCHEMBL115394 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TRPA1TRPM8EPHX1LMNA | |
| SCHEMBL21610687 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TRPA1TRPM8EPHX1LMNA | |
| SCHEMBL13206675 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TRPA1TRPM8EPHX1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445743-B1 | PRODRUG OF AMINO ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2021-08-04 | — | — | EP | disclosed |
| WO-2017183734-A1 | PRODRUG OF AMINO ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2017-10-26 | — | — | WO | disclosed |
| US-8242289-B2 | Alkyl-substituted tetrahydropyrans as flavoring substances | SYMRISE AG (DE) | 2012-08-14 | — | — | US | disclosed |
| US-20100226864-A1 | ALKYL-SUBSTITUTED TETRAHYDROPYRANS AS FLAVORING SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100226864-A1 | ALKYL-SUBSTITUTED TETRAHYDROPYRANS AS FLAVORING SUBSTANCES | TAS1R3, TAS2R10, TAS2R50 | ALDH1A1 69/4885TRPA1 25/4885TRPM8 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.