Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27767877 | 0.96 | EPHX1 (0.31) | EPHX1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL6428582 | 0.89 | MAPT (0.33) | MAPT | |
| Hydrochloric Acid SCHEMBL27567194 | 0.87 | MAPT (0.33) | MAPT | |
| SCHEMBL18480410 | 0.86 | EPHX1 (0.32) | EPHX1 | |
| Betaine SCHEMBL1302591 | 0.84 | TSHR (0.45) | — | |
| Water SCHEMBL4106014 | 0.84 | GAA (0.40) | HPGD | |
| Water SCHEMBL3597496 | 0.80 | MEN1 (0.39) | — | |
| SCHEMBL12866625 | 0.79 | CA1 (0.51) | — | |
| Water SCHEMBL3635067 | 0.78 | — | — | |
| SCHEMBL2888595 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119824421-A | Molybdenum etching solution | 湖北兴福电子材料股份有限公司 | 2025-04-15 | — | — | CN | claimed |
| US-12150375-B2 | Dipolar molecule stabilized perovskite material and optoelectronic devices | ZHEJIANG UNIVERSITY (CN) | 2024-11-19 | — | — | US | claimed |
| US-20240150309-A1 | GRISEOFULVIN COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2024-05-09 | — | — | US | claimed |
| US-20240090317-A1 | PEROVSKITE MATERIAL WITH STABLE BIPOLAR MOLECULES AND PHOTOELECTRIC DEVICE | ZHEJIANG UNIVERSITY (CN) | 2024-03-14 | — | — | US | claimed |
| CN-114220937-B | Bipolar molecular stable perovskite material and photoelectric device | 浙江大学 | 2023-08-29 | — | — | CN | claimed |
| WO-2023098926-A2 | PEROVSKITE MATERIAL HAVING STABLE BIPOLAR MOLECULES AND OPTOELECTRONIC DEVICE | 浙江大学 | 2023-06-08 | — | — | WO | claimed |
| CN-116159445-A | Polyamide composite membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-114220937-A | Bipolar molecular stable perovskite material and photoelectric device | 浙江大学 | 2022-03-22 | — | — | CN | claimed |
| EP-2781522-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUND, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND USING SAID CATALYST | Sumitomo Chemical Company, Limited (JP) | 2014-09-24 | — | — | EP | claimed |
| US-7579349-B2 | 4-(pyrazol-3-ylamino) pyrimidine derivatives for use in the treatment of cancer | ASTRAZENECA AB (SE) | 2009-08-25 | — | — | US | claimed |
| US-6414156-B2 | EFFICENT, NOTOXIC PROCESS OF MAKING NEW KEY INTERMEDIATE QUATERNARY AMMONIUM SALTS AND 2-OXAZOLYLALKYL SULFIDE DERIVATIVES AND AVOIDS THE REACTION OF A-HALOKETONES WITH AN AZIDE FOLLOWED BY REDUCING THE RESULTING A-AMINOKETONE | BRISTOL-MYERS SQUIBB COMPANY | 2002-07-02 | — | — | US | claimed |
| WO-2002010163-A1 | PROCESS FOR PREPARING AZACYCLOALKANOYLAMINOTHIAZOLES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-02-07 | — | — | WO | claimed |
| US-20010006976-A1 | Process for preparing azacycloalkanoylaminothiazoles | BRISTOL-MYERS SQUIBB COMPANY | 2001-07-05 | — | — | US | claimed |
| US-6008225-A | AN ANTIMICROBIAL AGENTS AGAINST GRAM POSITIVE BACTERIA INFECTIONS | BIOSEARCH ITALIA, S.P.A. (IT) | 1999-12-28 | — | — | US | claimed |
| EP-0880541-A1 | DERIVATIVES OF ANTIBIOTIC GE2270 FACTORS | Biosearch Italia S.p.A. (IT) | 1998-12-02 | — | — | EP | claimed |
| EP-0808326-A1 | BASIC OXAZOLINE-AMIDE DERIVATIVES OF GE 2270 AND GE 2270-LIKE ANTIBIOTICS | Biosearch Italia S.p.A. (IT) | 1997-11-26 | — | — | EP | claimed |
| EP-0801655-A1 | BASIC PROLINE-AMIDE DERIVATIVES OF GE 2270 AND GE 2270-LIKE ANTIBIOTICS | Biosearch Italia S.p.A. (IT) | 1997-10-22 | — | — | EP | claimed |
| WO-1997030078-A1 | DERIVATIVES OF ANTIBIOTIC GE2270 FACTORS C2a, D2 AND E | BIOSEARCH ITALIA S.P.A. (IT) | 1997-08-21 | — | — | WO | claimed |
| WO-1996024608-A1 | BASIC OXAZOLINE-AMIDE DERIVATIVES OF GE 2270 AND GE 2270-LIKE ANTIBIOTICS | BIOSEARCH ITALIA S.P.A. (IT) | 1996-08-15 | — | — | WO | claimed |
| WO-1996024607-A1 | BASIC PROLINE-AMIDE DERIVATIVES OF GE 2270 AND GE 2270-LIKE ANTIBIOTICS | BIOSEARCH ITALIA S.P.A. (IT) | 1996-08-15 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010006976-A1 | Process for preparing azacycloalkanoylaminothiazoles | CDK9, CDK4, CDK6 | EPHX1 3385/4885MAPT 3360/4885HPGD 3475/4885 |
| US-20240150309-A1 | GRISEOFULVIN COMPOUND | PTGS1, CYP11B1, GRIA1 | EPHX1 1814/4885MAPT 3099/4885HPGD 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.