Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842494 | 0.84 | ALDH1A1 (0.62) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR | |
| SCHEMBL11672909 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR | |
| SCHEMBL11845170 | 0.81 | HRH2 (0.49) | ALDH1A1TDP1ADAMTS4MAPTLMNA | |
| SCHEMBL11839171 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR | |
| SCHEMBL11847781 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR | |
| Bicarbonate SCHEMBL27502524 | 0.79 | ALDH1A1 (0.88) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR | |
| SCHEMBL2958562 | 0.77 | ALDH1A1 (0.92) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR | |
| SCHEMBL14494913 | 0.77 | ALDH1A1 (0.61) | ALDH1A1TDP1ADAMTS4CYP1A2PTPN1 | |
| SCHEMBL11829509 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR | |
| SCHEMBL11830726 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TDP1ADAMTS4CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969401-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | WILLIAM H. RORER, INC. (US) | 1976-07-13 | — | — | US | disclosed |
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |