Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11804211 | 0.84 | ALDH1A1 (0.44) | NR4A2ALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL17249871 | 0.84 | NR4A2 (0.53) | NR4A2ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL11789141 | 0.83 | IMPDH2 (0.53) | ALDH1A1KDM4EHSD17B10KMT2AMAPT | |
| SCHEMBL11787641 | 0.83 | ALDH1A1 (0.41) | NR4A2ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL11794579 | 0.82 | NR4A2 (0.46) | NR4A2ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL11281530 | 0.79 | IMPDH2 (0.54) | ALDH1A1KDM4EHSD17B10MAPTLMNA | |
| SCHEMBL11784891 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10KMT2AMAPT | |
| SCHEMBL2647337 | 0.76 | ALDH1A1 (0.47) | NR4A2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL4923169 | 0.76 | ALDH1A1 (0.47) | NR4A2ALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL400760 | 0.73 | NR4A2 (0.48) | NR4A2ALDH1A1KDM4EHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994899-A | METHINE | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
| US-3972880-A | TRANQUILIZER | SHARPS ASSOCIATES (US) | 1976-08-03 | — | — | US | disclosed |