Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11804211 | 0.84 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL11789141 | 0.83 | IMPDH2 (0.53) | ALDH1A1KDM4EHSD17B10KMT2ALMNA | |
| SCHEMBL11790699 | 0.83 | NR4A2 (0.45) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL11281530 | 0.79 | IMPDH2 (0.54) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL24329232 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10MEN1AHR | |
| SCHEMBL29583234 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10MEN1AHR | |
| SCHEMBL11784891 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL2647337 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL31287979 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10KMT2ALMNA | |
| SCHEMBL4825804 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994899-A | METHINE | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |