Permethrin

Permethrin

SCHEMBL117908

CC1(C)[C@H](C=C(Cl)Cl)[C@H]1C(=O)OCc1cccc(Oc2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

vssc

The experimentally established mechanism targets of Permethrin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 1.00
LMNA P02545 2/20 1.00
ADRA2A P08913 1/20 1.00
CNR1 P21554 1/20 1.00
ATM Q13315 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
ALDH1A1 P00352 1/20 0.58
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
FKBP1A P62942 3/20 0.45
MMP1 P03956 2/20 0.45
TSHR P16473 1/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
MMP12 P39900 1/20 0.44
CETP P11597 1/20 0.42
FFAR1 O14842 3/20 0.41
FFAR4 Q5NUL3 2/20 0.41
CCR8 P51685 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Permethrin SCHEMBL29397229 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Permethrin SCHEMBL29442911 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Permethrin SCHEMBL9665188 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Permethrin SCHEMBL9669087 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Permethrin SCHEMBL910678 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Permethrin SCHEMBL24089572 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Permethrin SCHEMBL9754130 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Permethrin SCHEMBL26543 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Permethrin SCHEMBL121233 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Permethrin SCHEMBL584812 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7651 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
WO-2025244856-A1 METHODS AND COMPOSITIONS RELATING TO ELQ COMPOUNDS OREGON HEALTH & SCIENCE UNIVERSITY (US) 2025-11-27 WO claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-4646109-A2 NATURAL LIPID PARTICLE FORMULATIONS FOR AGRICULTURAL APPLICATIONS Invaio Sciences, Inc. (US) 2025-11-12 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
US-20250324983-A1 METHOD AND APPARATUS FOR CONTROLLING ARTHROPODS USING MASSOIA ESSENTIAL OIL AND RELATED PYRONES US AGRICULTURE (US) 2025-10-23 US claimed
EP-4627920-A1 BINARY INSECTICIDE COMPOSITION AND USE THEREOF Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) 2025-10-08 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
US-20250143292-A1 STABLE CO-FORMULATION OF BENZOYLUREA WITH PYRETHROIDS UPL LTD (IN) 2025-05-08 US claimed
WO-1999008527-A1 COMPOSITIONS FOR TREATING TEXTILE AND PLASTIC ANTIMICROBIAL FINISH, AND USE OF SAME SANITIZED AG (CH) 1999-02-25 WO claimed
US-5194264-A Insecticides and miticides with pyrethoids, amidines, chlormethiuron, cyromazine and s-methoprene in solvents SCIENTIFIC CHEMICALS (PROPRIETARY) LIMITED (ZA) 1993-03-16 US claimed
US-5130135-A Pyrethroids as insecticides SMITHKLINE BEECHAM PLC (GB) 1992-07-14 US claimed
EP-0413610-A2 Pesticidal formulations PFIZER INC. (US) 1991-02-20 EP claimed
US-4670246-A INSECTICIDES PENNWALT CORPORATION (US) 1987-06-02 US claimed
EP-0183999-A1 Microencapsulated Pyrethroids ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) 1986-06-11 EP claimed
US-4515768-A STABILIZER AGAINST THERMAL DECOMPOSITION AIRWICK INDUSTRIES, INC. (US) 1985-05-07 US claimed
EP-0036385-B1 INSECTICIDAL VAPOUR-EMITTING COMPOSITIONS ON THE BASIS OF PYRETHRINOIDS Airwick AG (CH) 1984-05-02 EP claimed
EP-0036385-A2 Insecticidal vapour-emitting compositions on the basis of pyrethrinoids Airwick AG (CH) 1981-09-23 EP claimed
US-4100297-A CHRYSANTHEMIC ACID DERIVATIVES ROUSSEL UCLAF (FR) 1978-07-11 US claimed